Gene
zdhhc20b
- ID
- ZDB-GENE-091117-30
- Name
- zDHHC palmitoyltransferase 20b
- Symbol
- zdhhc20b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein palmitoylation; protein targeting to membrane; and synaptic vesicle maturation. Predicted to be located in several cellular components, including bounding membrane of organelle; endoplasmic reticulum membrane; and perinuclear region of cytoplasm. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC20 (zinc finger DHHC-type palmitoyltransferase 20).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001594 | Palmitoyltransferase, DHHC domain |
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Domain Details Per Protein
| Protein | Length | Palmitoyltransferase, DHHC domain |
|---|---|---|
|
UniProtKB:A0A8M1PUY2
|
397 | |
|
UniProtKB:A0A8M2B9Q3
|
409 |
1 - 2 of 2
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zdhhc20b-201
(1)
|
Ensembl | 972 nt | ||
| mRNA |
zdhhc20b-202
(1)
|
Ensembl | 1,462 nt |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-11P10 | ZFIN Curated Data |
1 - 1 of 1
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001423810 (1) | |||
| Genomic | GenBank:CR383672 (1) | 231583 nt | ||
| Polypeptide | UniProtKB:A0A8M2B9Q3 (1) | 409 aa |
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Du, Z., Chen, X., Li, X., He, K., Ji, S., Shi, W., Hao, A. (2016) Protein palmitoylation activate zygotic gene expression during the maternal-to-zygotic transition. Biochemical and Biophysical Research Communications. 475(2):194-201
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Wang, C., Chen, X., Shi, W., Wang, F., Du, Z., Li, X., Yao, Y., Liu, T., Shao, T., Li, G., Hao, A. (2015) 2-bromopalmitate impairs neural stem/progenitor cell proliferation, promotes cell apoptosis and induces malformation in zebrafish embryonic brain. Neurotoxicology and teratology. 50:53-63
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