Gene

tnrc6bb.2

ID

ZDB-GENE-091117-15

Name

trinucleotide repeat containing adaptor 6Bb.2

Symbol

tnrc6bb.2 Nomenclature History

Previous Names

si:dkey-217f16.6

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have nucleic acid binding activity. Predicted to be involved in gene silencing by miRNA and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Predicted to localize to P-body and nucleoplasm.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tnrc6bb.2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Global developmental delay with speech and behavioral abnormalities	619243

Associated With tnrc6bb.2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR019486	Argonaute hook domain
Domain	IPR032226	TNRC6, PABC binding domain
Family	IPR052068	GW182 domain-containing protein
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Argonaute hook domain	GW182 domain-containing protein	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	TNRC6, PABC binding domain
UniProtKB:A0A8M9PGS9 InterPro	865
UniProtKB:A0A8M9PTX3 InterPro	836

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	si:dkey-217f16.6-201 (1) Ensembl	Ensembl	2,757 nt	Select Tool ZFIN BLAST
mRNA	si:dkey-217f16.6-202 (1) Ensembl	Ensembl	832 nt	Select Tool ZFIN BLAST
mRNA	si:dkey-217f16.6-203 (1) Ensembl	Ensembl	2,670 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations