Gene

stard13a

ID

ZDB-GENE-091116-18

Name

StAR related lipid transfer domain containing 13a

Symbol

stard13a Nomenclature History

Previous Names

si:dkeyp-5f12.1

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable GTPase activator activity. Predicted to be involved in actin cytoskeleton organization and regulation of Rho protein signal transduction. Predicted to act upstream of or within lipid transport and signal transduction. Orthologous to human STARD13 (StAR related lipid transfer domain containing 13).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa11032	Allele with one point mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With stard13a Human Ortholog

No data available

Associated With stard13a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000198	Rho GTPase-activating protein domain
Domain	IPR001660	Sterile alpha motif domain
Domain	IPR002913	START domain
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily

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Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M2BK03	InterPro	1098
UniProtKB:A0A8N7UVJ5	InterPro	1138
UniProtKB:A0A8M3B6F6	InterPro	1116
UniProtKB:A0A8M2BK22	InterPro	1060

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Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Genome Build: GRCz11Chromosome: 10

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	stard13a-201 (1) Ensembl	Ensembl	3,019 nt	Select Tool ZFIN BLAST
mRNA	stard13a-202 (1) Ensembl	Ensembl	3,354 nt	Select Tool ZFIN BLAST
mRNA	stard13a-203 (1) Ensembl	Ensembl	2,591 nt	Select Tool ZFIN BLAST
mRNA	stard13a-204 (1) Ensembl	Ensembl	396 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	DKEY-271N12	BX510654	ZFIN Curated Data
Contained in	BAC	DKEYP-5F12	BX293562	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:XM_005172729 (1)	4006 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX293562 (1)	183193 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A8N7UVJ5 (1)	1138 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	STARD13	13	Ensembl:ENSG00000133121 Gene:90627 HGNC:19164 OMIM:609866	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)
Mouse	Stard13	5	Ensembl:ENSMUSG00000016128 Gene:243362 MGI:2385331	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)

Citations

Include unpublished citations

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

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