Gene

rps6kb1a

ID

ZDB-GENE-091113-52

Name

ribosomal protein S6 kinase b, polypeptide 1a

Symbol

rps6kb1a Nomenclature History

Previous Names

im:7155962
si:dkey-149m16.2

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to act upstream of or within protein phosphorylation and signal transduction. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human RPS6KB1 (ribosomal protein S6 kinase B1) and RPS6KB2 (ribosomal protein S6 kinase B2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7155962 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rps6kb1a Human Ortholog

No data available

Associated With rps6kb1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR000961	AGC-kinase, C-terminal
Domain	IPR017892	Protein kinase, C-terminal
Family	IPR016238	Ribosomal protein S6 kinase
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily

Domain Details Per Protein

Protein	Length	AGC-kinase, C-terminal	Protein kinase, ATP binding site	Protein kinase, C-terminal	Protein kinase domain	Protein kinase-like domain superfamily	Ribosomal protein S6 kinase	Serine/threonine-protein kinase, active site
UniProtKB:A0A8N7UVV0 InterPro	506

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	rps6kb1a-201 (1) Ensembl	Ensembl		1,862 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations