Gene
si:dkey-84o3.2
- ID
- ZDB-GENE-091113-19
- Name
- si:dkey-84o3.2
- Symbol
- si:dkey-84o3.2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable serine-type endopeptidase activity. Predicted to be involved in positive regulation of apoptotic process and programmed cell death. Predicted to act upstream of or within proteolysis. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 8; Parkinson's disease; and motor neuron disease. Orthologous to human HTRA2 (HtrA serine peptidase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PDZ domain | PDZ domain 6 | PDZ superfamily | Peptidase S1C | Peptidase S1, PA clan |
|---|---|---|---|---|---|---|
|
UniProtKB:E9QFX7
|
209 | |||||
|
UniProtKB:E7F3J5
|
113 | |||||
|
UniProtKB:A0A8M9PUB5
|
199 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
htra2-202
(1)
|
Ensembl | 411 nt | ||
| mRNA |
si:dkey-84o3.2-001
(1)
|
Ensembl | 1,239 nt |
Interactions and Pathways
No data available
Plasmids
No data available