Gene

tnnt2b

ID
ZDB-GENE-091106-2
Name
troponin T type 2b (cardiac)
Symbol
tnnt2b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to contribute to calcium-dependent ATPase activity and tropomyosin binding activity. Predicted to be involved in cardiac muscle contraction; sarcomere organization; and skeletal muscle contraction. Predicted to localize to troponin complex. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNT2 (troponin T2, cardiac type).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tnnt2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
dilated cardiomyopathy 1D Alliance Cardiomyopathy, dilated, 1D 601494
dilated cardiomyopathy 1D Alliance Left ventricular noncompaction 6 601494
hypertrophic cardiomyopathy 2 Alliance Cardiomyopathy, hypertrophic, 2 115195
restrictive cardiomyopathy 3 Alliance Cardiomyopathy, familial restrictive, 3 612422
Associated With tnnt2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001978 Troponin
Family IPR027707 Troponin T
Homologous_superfamily IPR038077 Troponin domain superfamily
Domain Details Per Protein
Protein Length Troponin Troponin domain superfamily Troponin T
UniProtKB:A0A0R4I9S9 233
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations