Gene
tnnt2b
- ID
- ZDB-GENE-091106-2
- Name
- troponin T type 2b (cardiac)
- Symbol
- tnnt2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to contribute to calcium-dependent ATPase activity and tropomyosin binding activity. Predicted to be involved in cardiac muscle contraction; sarcomere organization; and skeletal muscle contraction. Predicted to localize to troponin complex. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNT2 (troponin T2, cardiac type).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 1D | Alliance | Cardiomyopathy, dilated, 1D | 601494 |
| dilated cardiomyopathy 1D | Alliance | Left ventricular noncompaction 6 | 601494 |
| hypertrophic cardiomyopathy 2 | Alliance | Cardiomyopathy, hypertrophic, 2 | 115195 |
| restrictive cardiomyopathy 3 | Alliance | Cardiomyopathy, familial restrictive, 3 | 612422 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Troponin | Troponin domain superfamily | Troponin T |
|---|---|---|---|---|
|
UniProtKB:A0A8M6Z708
|
243 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnnt2b-201
(1)
|
Ensembl | 1,162 nt |
Interactions and Pathways
No data available
Plasmids
No data available