Gene

tead1b

ID
ZDB-GENE-091013-5
Name
TEA domain family member 1b
Symbol
tead1b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in embryonic organ development; hippo signaling; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in membrane and nucleus. Predicted to be integral component of membrane. Predicted to be part of transcription regulator complex. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Orthologous to human TEAD1 (TEA domain transcription factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tead1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Sveinsson chorioretinal atrophy Alliance Sveinsson chorioretinal atrophy 108985
Associated With tead1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000818 TEA/ATTS domain
Domain IPR041086 YAP binding domain
Family IPR016361 Transcriptional enhancer factor, metazoa
Homologous_superfamily IPR038096 TEA/ATTS domain superfamily
Domain Details Per Protein
Protein Length TEA/ATTS domain TEA/ATTS domain superfamily Transcriptional enhancer factor, metazoa YAP binding domain
UniProtKB:A0A2R8QV85 390
UniProtKB:A0A2R8QJV4 385
UniProtKB:A0A2R8Q5S5 364
UniProtKB:A0A2R8QPG4 410
UniProtKB:F8W5M8 380
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations