Gene
unc119a1
- ID
- ZDB-GENE-090930-2
- Name
- unc-119 lipid binding chaperone a1
- Symbol
- unc119a1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have lipid binding activity. Predicted to be involved in several processes, including lipoprotein transport; negative regulation of endocytosis; and positive regulation of protein tyrosine kinase activity. Predicted to localize to intercellular bridge and microtubule cytoskeleton. Human ortholog(s) of this gene implicated in idiopathic CD4-positive T-lymphocytopenia. Is expressed in blood cell and vascular endothelium. Orthologous to human UNC119 (unc-119 lipid binding chaperone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cone-rod dystrophy 24 | Alliance | Cone-rod dystrophy 24 | 620342 |
| immunodeficiency 13 | Alliance | ?Immunodeficiency 13 | 615518 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GMP phosphodiesterase, delta subunit | GMP phosphodiesterase, delta subunit superfamily | Immunoglobulin E-set | PDE6D/unc-119 myristoyl-binding |
|---|---|---|---|---|---|
|
UniProtKB:F1QE32
|
204 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
unc119a-201
(1)
|
Ensembl | 1,219 nt | ||
| mRNA |
unc119a-202
(1)
|
Ensembl | 603 nt | ||
| mRNA |
unc119a-203
(1)
|
Ensembl | 609 nt | ||
| mRNA |
unc119a-204
(1)
|
Ensembl | 402 nt | ||
| mRNA |
unc119a-205
(1)
|
Ensembl | 534 nt |
Interactions and Pathways
No data available
Plasmids
No data available