Gene
dpp6a
- ID
- ZDB-GENE-090918-4
- Name
- dipeptidyl-peptidase 6a
- Symbol
- dpp6a Nomenclature History
- Previous Names
-
- si:ch211-232k18.1
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have serine-type peptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; autosomal dominant non-syndromic intellectual disability 33; and spinal muscular atrophy. Orthologous to human DPP6 (dipeptidyl peptidase like 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 33 | Alliance | Intellectual developmental disorder, autosomal dominant 33 | 616311 |
| {Ventricular fibrillation, paroxysmal familial, 2} | 612956 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Dipeptidylpeptidase IV, N-terminal domain | Peptidase S9, prolyl oligopeptidase, catalytic domain | Serine protease S9B/DPPIV |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PUA5
|
693 | ||||
|
UniProtKB:A0A8M3AP34
|
810 | ||||
|
UniProtKB:A0A0R4ISU8
|
800 | ||||
|
UniProtKB:A0A8M3AVW3
|
800 | ||||
|
UniProtKB:A0A8M3ANF1
|
798 |
Interactions and Pathways
No data available
Plasmids
No data available