Gene

nlgn2a

ID
ZDB-GENE-090918-2
Name
neuroligin 2a
Symbol
nlgn2a Nomenclature History
Previous Names
  • nlgn2b
  • nlgn2bl
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Is predicted to enable neurexin family protein binding activity and signaling receptor activity. Involved in several processes, including neuron cell-cell adhesion; synapse assembly; and synaptic vesicle endocytosis. Acts upstream of or within cell adhesion and synapse organization. Predicted to be located in inhibitory synapse and plasma membrane. Predicted to be integral component of membrane. Is expressed in digestive system; gill; gonad; heart; and nervous system. Orthologous to human NLGN2 (neuroligin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nlgn2a Human Ortholog
No data available
Associated With nlgn2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019819 Carboxylesterase type B, conserved site
Domain IPR002018 Carboxylesterase, type B
Family IPR000460 Neuroligin
Family IPR030023 Neuroligin-2
Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
Domain Details Per Protein
Protein Length Alpha/Beta hydrolase fold Carboxylesterase, type B Carboxylesterase type B, conserved site Neuroligin Neuroligin-2
UniProtKB:F1Q9C0 810
UniProtKB:D2X2G0 828
UniProtKB:D0EVX0 810
UniProtKB:F1QJV3 828
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations