Gene

plekhg2

ID
ZDB-GENE-090819-1
Name
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Symbol
plekhg2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to enable guanyl-nucleotide exchange factor activity. Orthologous to human PLEKHG2 (pleckstrin homology and RhoGEF domain containing G2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Wei et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plekhg2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Leukodystrophy and acquired microcephaly with or without dystonia 616763
Associated With plekhg2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000219 Dbl homology (DH) domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR043324 PKHG1/2/3, pleckstrin homology (PH) domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Domain Details Per Protein
Protein Length Dbl homology (DH) domain Dbl homology (DH) domain superfamily PH-like domain superfamily PKHG1/2/3, pleckstrin homology (PH) domain Pleckstrin homology domain
UniProtKB:X1WE43 2102
UniProtKB:A0A0R4IV58 1543
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations