Gene
tfeb
- ID
- ZDB-GENE-090807-3
- Name
- transcription factor EB
- Symbol
- tfeb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have protein dimerization activity. Involved in central nervous system myelination. Is expressed in several structures, including head; immature eye; mesoderm; pancreatic system; and pronephros. Orthologous to human TFEB (transcription factor EB).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Meireles et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
| Domain | IPR021802 | MiT/TFE transcription factors, C-terminal |
| Domain | IPR024098 | Transcription factor EB, bHLHzip domain |
| Domain | IPR031867 | MiT/TFE transcription factors, N-terminal |
| Homologous_superfamily | IPR036638 | Helix-loop-helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Helix-loop-helix DNA-binding domain superfamily | MiT/TFE transcription factors, C-terminal | MiT/TFE transcription factors, N-terminal | Myc-type, basic helix-loop-helix (bHLH) domain | Transcription factor EB, bHLHzip domain |
|---|---|---|---|---|---|---|
|
UniProtKB:E7FEM8
|
491 | |||||
|
UniProtKB:A0A8M9Q799
|
433 | |||||
|
UniProtKB:A0A2R8RRI1
|
493 | |||||
|
UniProtKB:A0A8M2BK54
|
325 | |||||
|
UniProtKB:G5CIM3
|
493 | |||||
|
UniProtKB:A0A8M2BK61
|
327 |
Interactions and Pathways
No data available
Plasmids