Gene
lyl1
- ID
- ZDB-GENE-090807-1
- Name
- LYL1 basic helix-loop-helix family member
- Symbol
- lyl1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia. Orthologous to human LYL1 (LYL1 basic helix-loop-helix family member).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Leukemia, T-cell acute lymphoblastoid | 151440 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Helix-loop-helix DNA-binding domain superfamily | Helix-loop-helix protein TAL-like | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|---|---|
| UniProtKB:A0A8M3B318 | InterPro | 323 | |||
| UniProtKB:A0A8M3ASZ4 | InterPro | 321 | |||
| UniProtKB:A0A8M3B043 | InterPro | 322 | |||
| UniProtKB:A0A8M3BA36 | InterPro | 320 | |||
| UniProtKB:A0A8M9Q014 | InterPro | 325 | |||
| UniProtKB:A0A8M3AT04 | InterPro | 326 | |||
| UniProtKB:A0AB32TQ46 | InterPro | 325 | |||
| UniProtKB:A0AB32TR49 | InterPro | 320 | |||
| UniProtKB:A0AB32TRC3 | InterPro | 321 | |||
| UniProtKB:A0AB32TTH5 | InterPro | 323 | |||
| UniProtKB:A0AB32TVF4 | InterPro | 322 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids