ZFIN ID: ZDB-GENE-090805-1
Gene Name: atonal bHLH transcription factor 1c
Gene Symbol: atoh1c    Nomenclature History

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Previous Name: Zath1c (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have protein dimerization activity and sequence-specific DNA binding activity. Involved in cerebellar granule cell differentiation. Is expressed in brain; midbrain hindbrain boundary neural rod; and midbrain hindbrain boundary neural tube. Orthologous to human ATOH1 (atonal bHLH transcription factor 1).
Genome Resources: Alliance (1),  Gene:100498672 (1),  Ensembl(GRCz11):ENSDARG00000039602 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh367 Small Deletion Unknown Premature Stop TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
TALEN1-atoh1c 1
DISEASE ASSOCIATED WITH atoh1c HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH atoh1c VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cerebellar granule cell differentiation (more)
Molecular Function protein dimerization activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR032661 Protein atonal homologue 1
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA atoh1c-201 (1)    Ensembl 776
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM atoh1c
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
TgBAC(atoh1c:GAL4FF) atoh1c GAL4FF Danio rerio 1 1
MARKER RELATIONSHIPS
atoh1c Contained in: [BAC] DKEY-257J3 (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_003199570 (1)
Genomic GenBank:CR792429 (1) 163868 bp
Select Tool
Polypeptide UniProtKB:F1Q7A7 (1) 204 aa
Sequence Information (all 11)
ORTHOLOGY for atoh1c ( Chr: 12 )
CITATIONS (16)