header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-090617-1
Gene Name: Nance-Horan syndrome a (congenital cataracts and dental anomalies)
Gene Symbol: nhsa
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name:

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to be involved in cell differentiation. Human ortholog(s) of this gene implicated in Nance-Horan syndrome and cataract 40. Orthologous to human NHS (NHS actin remodeling regulator).
GENE EXPRESSION
All Expression Data: Fig. S4 from Walsh et al., 2011
Wild-type Stages, Structures: Segmentation:10-13 somites (14.0h-16.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh298 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • fh299 Point Mutation Unknown Unknown ENU
    ihb87 Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb88 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb89 Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • la022748Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028572Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nhsa_unrecovered Point Mutation Unknown Unknown ENU
    sa11777 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17321 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nhsa HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cataract 40 Cataract 40, X-linked 302200
    Nance-Horan syndrome Nance-Horan syndrome 302350
    DISEASE ASSOCIATED WITH nhsa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell differentiation (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR024845 (1)
  • Pfam:PF15273 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nhsa No data available
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_001919305 (1) 7875bp
    Genomic GenBank:CABZ01056829 (1) 22993bp
    Polypeptide UniProtKB:E7FBZ1 (1) 1259aa
    Sequence Clusters UniGene:130281 (1)
    Sequence Information (all 39)
    ORTHOLOGY for nhsa (Chr: 23)
    CITATIONS (21)