Gene

doc2b

ID
ZDB-GENE-090615-1
Name
double C2-like domains, beta
Symbol
doc2b Nomenclature History
Previous Names
  • WITHDRAWN: wu:fb11f01
  • wu:fb11f01
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable metal ion binding activity and small GTPase binding activity. Predicted to be involved in calcium-dependent activation of synaptic vesicle fusion and positive regulation of calcium ion-dependent exocytosis. Predicted to act upstream of or within intracellular protein transport. Predicted to be located in membrane. Predicted to be active in synapse. Orthologous to human DOC2B (double C2 domain beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
nf4Allele with one deletionUnknownUnknownCRISPR
sa33740Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With doc2b Human Ortholog
No data available
Associated With doc2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000008 C2 domain
Domain IPR001565 Synaptotagmin
Domain IPR010911 Rab-binding domain
Domain IPR017455 Zinc finger, FYVE-related
Domain IPR041282 FYVE-type zinc finger
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Domain Details Per Protein
Protein Additional Resources Length C2 domain C2 domain superfamily Double C2 protein, alpha/beta/gamma FYVE-type zinc finger Rab-binding domain Rabphilin/Doc2, first C2 domain Rabphilin/Doc2/Noc2 Synaptotagmin Zinc finger, FYVE/PHD-type Zinc finger, FYVE-related Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A8M3B9Z3 InterPro 593
UniProtKB:A0A8M3ASV5 InterPro 396
UniProtKB:A0A2R8QNT0 InterPro 640
UniProtKB:A0A8M6YYK0 InterPro 648
UniProtKB:A0AB32TSI5 InterPro 404
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA doc2b-201 (1)
Ensembl
Ensembl 773 nt
ZFIN BLAST
mRNA doc2b-202 (1)
Ensembl
Ensembl 2,080 nt
ZFIN BLAST
mRNA doc2b-203 (1)
Ensembl
Ensembl 2,306 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-195M10ZFIN Curated Data
ContainsSNPrs3728535
    ContainsSNPrs3728536
      Has ArtifactESTfb11f01
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      Sequences
      Type Accession # Sequence Length (nt/aa) Analysis
      RNARefSeq:XM_017356366 (1)4738 nt
      ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
      GenomicGenBank:CR932980 (1)253220 nt
      MegaBLAST
      PolypeptideUniProtKB:A0A8M6YYK0 (1)648 aa
      ZFIN BLASTSIB BLASTEnsembl Protein Blast
      Orthology
      Comparative Orthology
      Alliance
      Gene Tree
      Ensembl
      No data available
      Citations
      TSV
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