Gene
cngb3.1
- ID
- ZDB-GENE-090611-1
- Name
- cyclic nucleotide gated channel subunit beta 3, tandem duplicate 1
- Symbol
- cngb3.1 Nomenclature History
- Previous Names
-
- cngb3
- si:ch211-189o17.7
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in cation transmembrane transport and visual perception. Human ortholog(s) of this gene implicated in achromatopsia 3 and color blindness. Orthologous to human CNGB3 (cyclic nucleotide gated channel subunit beta 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| achromatopsia 3 | Alliance | Achromatopsia 3 | 262300 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018488 | Cyclic nucleotide-binding, conserved site |
| Domain | IPR000595 | Cyclic nucleotide-binding domain |
| Family | IPR050866 | Cyclic nucleotide-gated cation channel |
| Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
| Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Cyclic nucleotide-binding, conserved site | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | Cyclic nucleotide-gated cation channel | RmlC-like jelly roll fold |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PX95
|
787 | |||||
|
UniProtKB:A0A8M3AZ92
|
793 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cngb3.1-201
(1)
|
Ensembl | 2,783 nt | ||
| mRNA |
cngb3.1-202
(1)
|
Ensembl | 2,157 nt |
Interactions and Pathways
No data available
Plasmids
No data available