Gene

cep43

ID

ZDB-GENE-090417-1

Name

centrosomal protein 43

Symbol

cep43 Nomenclature History

Previous Names

fgfr1op
zgc:86782 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable calcium ion binding activity. Predicted to act upstream of or within cell projection organization and microtubule anchoring. Predicted to be located in cell projection; cytoplasm; and microtubule organizing center. Predicted to be active in centrosome. Orthologous to human CEP43 (centrosomal protein 43).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cep43 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Myeloproliferative disorder	605392

Associated With cep43 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR006594	LIS1 homology motif
Domain	IPR002048	EF-hand domain
Domain	IPR018993	FGFR1 oncogene partner (FOP), N-terminal dimerisation domain
Homologous_superfamily	IPR011992	EF-hand domain pair

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PP81	InterPro	557
UniProtKB:A0A0R4IW74	InterPro	487
UniProtKB:A0A8M2B7I9	InterPro	508
UniProtKB:A0A8M9PBN5	InterPro	515
UniProtKB:Q6IQF6	InterPro	511
UniProtKB:A0A8M9PSK8	InterPro	563
UniProtKB:A0A8M2B7J0	InterPro	538
UniProtKB:A0A8M9P2I3	InterPro	542
UniProtKB:A0A8M6YUS2	InterPro	485
UniProtKB:A0AB32TDN6	InterPro	464
UniProtKB:A0AB32TDP7	InterPro	532
UniProtKB:A0AB32TF59	InterPro	502

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fgfr1op-201 (1) Ensembl	Ensembl	1,668 nt	Select Tool ZFIN BLAST
mRNA	fgfr1op-204 (1) Ensembl	Ensembl	695 nt	Select Tool ZFIN BLAST
mRNA	fgfr1op-205 (1) Ensembl	Ensembl	2,319 nt	Select Tool ZFIN BLAST
ncRNA	fgfr1op-002 (1) Ensembl	Ensembl	619 nt	Select Tool ZFIN BLAST
ncRNA	fgfr1op-003 (1) Ensembl	Ensembl	588 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations