Gene
chrm2b
- ID
- ZDB-GENE-090410-3
- Name
- cholinergic receptor, muscarinic 2b
- Symbol
- chrm2b Nomenclature History
- Previous Names
-
- si:dkeyp-8b11.3
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled acetylcholine receptor activity and G protein-coupled serotonin receptor activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway and chemical synaptic transmission. Predicted to localize to dendrite; integral component of plasma membrane; and synapse. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; asthma; bipolar disorder; heroin dependence; and major depressive disorder. Orthologous to human CHRM2 (cholinergic receptor muscarinic 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Muscarinic acetylcholine receptor family |
|---|---|---|---|---|
|
UniProtKB:A0A8M9Q5D6
|
476 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
chrm2b-202
(1)
|
Ensembl | 1,401 nt | ||
| mRNA |
chrm2b-203
(1)
|
Ensembl | 6,272 nt |
Interactions and Pathways
No data available
Plasmids
No data available