Gene

ptpn20

ID

ZDB-GENE-090313-90

Name

protein tyrosine phosphatase non-receptor type 20

Symbol

ptpn20 Nomenclature History

Previous Names

si:ch211-223a10.7

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to enable protein tyrosine phosphatase activity. Predicted to act upstream of or within bicellular tight junction assembly and protein dephosphorylation. Predicted to be located in cytoskeleton. Orthologous to human PTPN20 (protein tyrosine phosphatase non-receptor type 20).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from van Eekelen et al., 2010

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptpn20 Human Ortholog

No data available

Associated With ptpn20 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000299	FERM domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR001478	PDZ domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR011019	KIND domain
Domain	IPR018979	FERM, N-terminal
Domain	IPR018980	FERM, C-terminal PH-like domain
Domain	IPR019748	FERM central domain
Domain	IPR019749	Band 4.1 domain
Family	IPR052074	Non-receptor Tyrosine-protein Phosphatases
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR014352	FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR035963	FERM superfamily, second domain
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	Band 4.1 domain	FERM/acyl-CoA-binding protein superfamily	FERM central domain	FERM, C-terminal PH-like domain	FERM domain	FERM, N-terminal	FERM superfamily, second domain	KIND domain	Non-receptor Tyrosine-protein Phosphatases	PDZ domain	PDZ superfamily	PH-like domain superfamily	Protein kinase-like domain superfamily	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Tyrosine-specific protein phosphatase, PTPase domain	Tyrosine-specific protein phosphatases domain	Ubiquitin-like domain superfamily
UniProtKB:A0A8M3B859 InterPro	2187
UniProtKB:A0A8M3AZB5 InterPro	1841
UniProtKB:A0A8M3B5D6 InterPro	2167
UniProtKB:A0A8M9QNW1 InterPro	552
UniProtKB:A0A8M3AZ90 InterPro	2195

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ptpn20-201 (1) Ensembl	Ensembl	1,216 nt	Select Tool ZFIN BLAST
mRNA	ptpn20-202 (1) Ensembl	Ensembl	1,118 nt	Select Tool ZFIN BLAST
mRNA	ptpn20-203 (1) Ensembl	Ensembl	615 nt	Select Tool ZFIN BLAST
mRNA	ptpn20-204 (1) Ensembl	Ensembl	280 nt	Select Tool ZFIN BLAST
mRNA	ptpn20-205 (1) Ensembl	Ensembl	381 nt	Select Tool ZFIN BLAST
mRNA	ptpn20-206 (1) Ensembl	Ensembl	265 nt	Select Tool ZFIN BLAST
mRNA	ptpn20-207 (1) Ensembl	Ensembl	857 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations