Gene
arhgef38
- ID
- ZDB-GENE-090313-83
- Name
- Rho guanine nucleotide exchange factor (GEF) 38
- Symbol
- arhgef38 Nomenclature History
- Previous Names
-
- si:ch211-216c6.3
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction. Predicted to localize to cytoplasm. Orthologous to human ARHGEF38 (Rho guanine nucleotide exchange factor 38).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lansdon et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR004148 | BAR domain |
| Family | IPR051492 | Dynamin-binding and Rho GEF |
| Homologous_superfamily | IPR027267 | AH/BAR domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | BAR domain | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | Dynamin-binding and Rho GEF | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3ASM7
|
762 | ||||||||
|
UniProtKB:A0A8M3AIF8
|
548 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arhgef38-201
(1)
|
Ensembl | 2,764 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance