Gene
coa8
- ID
- ZDB-GENE-090313-66
- Name
- cytochrome c oxidase assembly factor 8
- Symbol
- coa8 Nomenclature History
- Previous Names
-
- apopt1
- si:ch211-194h13.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within intrinsic apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COA8 (cytochrome c oxidase assembly factor 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 17 | Alliance | Mitochondrial complex IV deficiency, nuclear type 17 | 619061 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR018796 | Cytochrome c oxidase assembly factor 8 |
Domain Details Per Protein
| Protein | Length | Cytochrome c oxidase assembly factor 8 |
|---|---|---|
|
UniProtKB:B8A5M9
|
205 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
apopt1-201
(1)
|
Ensembl | 1,249 nt |
Interactions and Pathways
No data available
Plasmids
No data available