Gene
gp9
- ID
- ZDB-GENE-090313-5
- Name
- glycoprotein IX platelet
- Symbol
- gp9 Nomenclature History
- Previous Names
-
- si:ch1073-66c17.4
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Acts upstream of or within regulation of blood coagulation and thrombocyte differentiation. Used to study Bernard-Soulier syndrome. Human ortholog(s) of this gene implicated in Bernard-Soulier syndrome. Orthologous to human GP9 (glycoprotein IX platelet).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Lin et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Lin et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sm17 | Allele with one deletion | Exon 2 | Unknown | CRISPR |
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Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bernard-Soulier syndrome | Alliance | Bernard-Soulier syndrome, type C | 231200 |
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| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Bernard-Soulier syndrome | gp9sm17/sm17; la2Tg | standard conditions | Lin et al., 2021 |
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Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | Fosmid | CH1073-66C17 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| Genomic | GenBank:CU571070 | 40511 nt |
- Lin, Q., Zhou, R., Meng, P., Wu, L., Yang, L., Liu, W., Wu, J., Cheng, Y., Shi, L., Zhang, Y. (2021) Establishment of a Bernard-Soulier syndrome model in zebrafish. Haematologica. 107(7):1655-1668
- Lin, Q., Zhang, Y., Zhou, R., Zheng, Y., Zhao, L., Huang, M., Zhang, X., Leung, A.Y., Zhang, W., Zhang, Y. (2017) Establishment of a congenital amegakaryocytic thrombocytopenia model and a thrombocyte-specific reporter line in zebrafish. Leukemia. 31(5):1206-1216
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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