Gene

wfdc2

ID

ZDB-GENE-090313-47

Name

WAP four-disulfide core domain 2

Symbol

wfdc2 Nomenclature History

Previous Names

si:ch211-153a8.3

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable peptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be located in extracellular region. Orthologous to several human genes including WFDC3 (WAP four-disulfide core domain 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Mitchell et al., 2021

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With wfdc2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Bronchiectasis and nasal polyposis	620984

Associated With wfdc2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR008197	WAP-type 'four-disulfide core' domain
Family	IPR050514	WAP four-disulfide core domain
Homologous_superfamily	IPR036645	Elafin-like superfamily