Gene
si:dkey-219c3.2
- ID
- ZDB-GENE-090313-238
- Name
- si:dkey-219c3.2
- Symbol
- si:dkey-219c3.2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to act upstream of or within DNA-templated transcription initiation. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la023209Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa17606 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa17763 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa24669 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa38065 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003894 | TAFH/NHR1 |
| Domain | IPR007900 | Transcription initiation factor TFIID component TAF4, C-terminal |
| Family | IPR045144 | Transcription initiation factor TFIID component TAF4 |
| Homologous_superfamily | IPR009072 | Histone-fold |
| Homologous_superfamily | IPR037249 | TAFH/NHR1 domain superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Histone-fold | TAFH/NHR1 | TAFH/NHR1 domain superfamily | Transcription initiation factor TFIID component TAF4 | Transcription initiation factor TFIID component TAF4, C-terminal |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z4F3 | InterPro | 975 | |||||
| UniProtKB:E7FFQ2 | InterPro | 976 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-219c3.2-201
(1)
|
Ensembl | 2,946 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-219C3 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005163068 (1) | |||
| Genomic | GenBank:BX927360 (1) | 92192 nt | ||
| Polypeptide | UniProtKB:E7FFQ2 (1) | 976 aa |
No data available
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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