Gene
prepl
- ID
- ZDB-GENE-090313-224
- Name
- prolyl endopeptidase like
- Symbol
- prepl Nomenclature History
- Previous Names
-
- si:dkey-202m23.1
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable serine-type endopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be active in Golgi apparatus and cytoskeleton. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 22. Orthologous to human PREPL (prolyl endopeptidase like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital myasthenic syndrome 22 | Alliance | Myasthenic syndrome, congenital, 22 | 616224 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001375 | Peptidase S9, prolyl oligopeptidase, catalytic domain |
| Domain | IPR023302 | Peptidase S9A, N-terminal domain |
| Family | IPR002470 | Peptidase S9A, prolyl oligopeptidase |
| Family | IPR051543 | Serine Peptidase S9A Subfamily |
| Homologous_superfamily | IPR029058 | Alpha/Beta hydrolase fold |
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Peptidase S9A, N-terminal domain | Peptidase S9A, prolyl oligopeptidase | Peptidase S9, prolyl oligopeptidase, catalytic domain | Serine Peptidase S9A Subfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B2W4
|
672 | |||||
|
UniProtKB:B8JJX2
|
692 |
Interactions and Pathways
No data available
Plasmids
No data available