rasa3

ID

ZDB-GENE-090313-21

Name

RAS p21 protein activator 3

Symbol

rasa3 Nomenclature History

Previous Names

si:ch211-129c2.7

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable GTPase activator activity and metal ion binding activity. Acts upstream of or within blood vessel lumenization; nucleate erythrocyte differentiation; and thrombocyte differentiation. Is expressed in central nervous system. Orthologous to human RASA3 (RAS p21 protein activator 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Blanc et al., 2012

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rasa3 Human Ortholog

No data available

Associated With rasa3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001562	Zinc finger, Btk motif
Conserved_site	IPR023152	Ras GTPase-activating protein, conserved site
Domain	IPR000008	C2 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR001936	Ras GTPase-activating domain
Domain	IPR037774	RASA3, PH domain
Family	IPR039360	Ras GTPase-activating protein
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR035892	C2 domain superfamily