Gene

rims1b

ID

ZDB-GENE-101223-4

Name

regulating synaptic membrane exocytosis 1b

Symbol

rims1b Nomenclature History

Previous Names

rims1
si:dkey-179o14.1

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have Rab GTPase binding activity and ion channel binding activity. Predicted to be involved in calcium ion-regulated exocytosis of neurotransmitter; modulation of chemical synaptic transmission; and regulation of membrane potential. Predicted to localize to cytoskeleton of presynaptic active zone and presynaptic membrane. Human ortholog(s) of this gene implicated in cone-rod dystrophy 7. Orthologous to human RIMS1 (regulating synaptic membrane exocytosis 1).

Genome Resources

Note

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rims1b Human Ortholog

No data available

Associated With rims1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000008	C2 domain
Domain	IPR001478	PDZ domain
Domain	IPR010911	Rab-binding domain
Domain	IPR017455	Zinc finger, FYVE-related
Domain	IPR054386	RIM, zinc finger
Family	IPR039032	Rim-like
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR035892	C2 domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	C2 domain	C2 domain superfamily	PDZ domain	PDZ superfamily	Rab-binding domain	Rim-like	RIM, zinc finger	Zinc finger, FYVE/PHD-type	Zinc finger, FYVE-related	Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A8N7TFK0 InterPro	559
UniProtKB:A0A8M9Q519 InterPro	1602

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	rims1b-201 (1) Ensembl	Ensembl		4,065 nt	Select Tool ZFIN BLAST
mRNA	rims1b-202 (1) Ensembl	Ensembl		778 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations