Gene
rims1b
- ID
- ZDB-GENE-101223-4
- Name
- regulating synaptic membrane exocytosis 1b
- Symbol
- rims1b Nomenclature History
- Previous Names
-
- rims1
- si:dkey-179o14.1
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable transmembrane transporter binding activity. Predicted to be involved in calcium ion-regulated exocytosis of neurotransmitter; modulation of chemical synaptic transmission; and regulation of membrane potential. Predicted to act upstream of or within exocytosis and intracellular protein transport. Predicted to be located in membrane and synapse. Predicted to be active in cytoskeleton of presynaptic active zone and presynaptic membrane. Human ortholog(s) of this gene implicated in cone-rod dystrophy 7. Orthologous to human RIMS1 (regulating synaptic membrane exocytosis 1).
- Genome Resources
- Note
-
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR010911 | Rab-binding domain |
| Domain | IPR017455 | Zinc finger, FYVE-related |
| Domain | IPR054386 | RIM, zinc finger |
| Family | IPR039032 | Rim-like |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Length | C2 domain | C2 domain superfamily | PDZ domain | PDZ superfamily | Rab-binding domain | Rim-like | RIM, zinc finger | Zinc finger, FYVE/PHD-type | Zinc finger, FYVE-related | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8N7TFK0
|
559 | ||||||||||
|
UniProtKB:A0A8M9Q519
|
1602 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rims1b-201
(1)
|
Ensembl | 4,065 nt | ||
| mRNA |
rims1b-202
(1)
|
Ensembl | 778 nt |
Interactions and Pathways
No data available
Plasmids
No data available