Gene
tdrd9
- ID
- ZDB-GENE-090313-193
- Name
- tudor domain containing 9
- Symbol
- tdrd9 Nomenclature History
- Previous Names
-
- si:dkey-15f17.9 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable ATP hydrolysis activity; RNA binding activity; and helicase activity. Predicted to be involved in several processes, including male meiosis I; regulatory ncRNA-mediated gene silencing; and spermatogenesis. Predicted to act upstream of or within cell differentiation; meiotic cell cycle; and regulatory ncRNA-mediated gene silencing. Predicted to be located in piP-body. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spermatogenic failure 30. Orthologous to human TDRD9 (tudor domain containing 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spermatogenic failure 30 | Alliance | ?Spermatogenic failure 30 | 618110 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR002464 | DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR002999 | Tudor domain |
| Domain | IPR007502 | Helicase-associated domain |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR047384 | Tudor domain-containing protein 9, Tudor domain |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR035437 | SNase-like, OB-fold superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | DEAD/DEAH box helicase domain | DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site | Helicase-associated domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | SNase-like, OB-fold superfamily | Tudor domain | Tudor domain-containing protein 9, Tudor domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:B8A4F4 | InterPro | 1342 | |||||||||
| UniProtKB:A0AB32T0D8 | InterPro | 1344 |
Interactions and Pathways
No data available
Plasmids
No data available