Gene

chrna8

ID

ZDB-GENE-090313-161

Name

cholinergic receptor, nicotinic, alpha 8

Symbol

chrna8 Nomenclature History

Previous Names

si:ch73-380n15.2

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to contribute to acetylcholine receptor activity. Predicted to be involved in several processes, including cholinergic synaptic transmission; nervous system process; and regulation of membrane potential. Predicted to localize to acetylcholine-gated channel complex; neuron projection; and synapse.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With chrna8 Human Ortholog

No data available

Associated With chrna8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018000	Neurotransmitter-gated ion-channel, conserved site
Domain	IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
Domain	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
Family	IPR002394	Nicotinic acetylcholine receptor
Family	IPR006201	Neurotransmitter-gated ion-channel
Homologous_superfamily	IPR036719	Neurotransmitter-gated ion-channel transmembrane domain superfamily
Homologous_superfamily	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Homologous_superfamily	IPR038050	Neuronal acetylcholine receptor

Domain Details Per Protein

Protein	Length	Neuronal acetylcholine receptor	Neurotransmitter-gated ion-channel	Neurotransmitter-gated ion-channel, conserved site	Neurotransmitter-gated ion-channel ligand-binding domain	Neurotransmitter-gated ion-channel ligand-binding domain superfamily	Neurotransmitter-gated ion-channel transmembrane domain	Neurotransmitter-gated ion-channel transmembrane domain superfamily	Nicotinic acetylcholine receptor
UniProtKB:A0A8M9PPT6 InterPro	329
UniProtKB:A0A8M9PEJ8 InterPro	516

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	si:ch73-380n15.2-201 (1) Ensembl	Ensembl		423 nt	Select Tool ZFIN BLAST
mRNA	si:ch73-380n15.2-202 (1) Ensembl	Ensembl		1,530 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations