Gene

tet1

ID
ZDB-GENE-090312-88
Name
tet methylcytosine dioxygenase 1
Symbol
tet1 Nomenclature History
Previous Names
  • tet3 (1)
  • si:dkey-228d14.7 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have iron ion binding activity and methylcytosine dioxygenase activity. Involved in cellular response to lipopolysaccharide; regulation of interleukin-13 biosynthetic process; and response to hypoxia. Predicted to localize to nucleus. Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region. Orthologous to human TET1 (tet methylcytosine dioxygenase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Wang et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tet1 Human Ortholog
No data available
Associated With tet1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002857 Zinc finger, CXXC-type
Domain IPR024779 2OGFeDO JBP1/TET, oxygenase domain
Domain IPR046942 Methylcytosine dioxygenase TET1-3, oxygenase domain
Family IPR040175 Methylcytosine dioxygenase TET1/2/3
Domain Details Per Protein
Protein Length 2OGFeDO JBP1/TET, oxygenase domain Methylcytosine dioxygenase TET1/2/3 Methylcytosine dioxygenase TET1-3, oxygenase domain Zinc finger, CXXC-type
UniProtKB:A0A8M9Q186 1812
UniProtKB:A0A8M3AZ15 1370
UniProtKB:F1R3C6 1855
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tet1-201 (1) Ensembl 5,568 nt
mRNA tet1-202 (1) Ensembl 1,677 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations