ZFIN is now using GRCz12tu for Genomic Data
Gene
camk2b2
- ID
- ZDB-GENE-090312-34
- Name
- calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
- Symbol
- camk2b2 Nomenclature History
- Previous Names
-
- si:dkey-259k14.5
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Predicted to be involved in regulation of neuronal synaptic plasticity and regulation of protein localization to plasma membrane. Predicted to be located in organelle. Predicted to be active in cytoplasm; neuron projection; and postsynaptic density. Is expressed in brain; pectoral fin; pericardial region; somite; and tail bud.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 54 | Alliance | Intellectual developmental disorder, autosomal dominant 54 | 617799 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR013543 | Calcium/calmodulin-dependent protein kinase II, association-domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR032710 | NTF2-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Calcium/calmodulin-dependent protein kinase II, association-domain | NTF2-like domain superfamily | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QCS7 | InterPro | 476 | |||||
| UniProtKB:A0A8M9QHD1 | InterPro | 516 | |||||
| UniProtKB:A0A8M9QHD4 | InterPro | 501 | |||||
| UniProtKB:A0A8M9QLC5 | InterPro | 536 | |||||
| UniProtKB:A0A8M9QLC8 | InterPro | 521 | |||||
| UniProtKB:A0A8M1PUN4 | InterPro | 517 | |||||
| UniProtKB:A0A8M2B1J9 | InterPro | 492 | |||||
| UniProtKB:A0A8M2B1Y8 | InterPro | 477 | |||||
| UniProtKB:A0A8M3AX87 | InterPro | 512 | |||||
| UniProtKB:A0A8M3AXB0 | InterPro | 537 | |||||
| UniProtKB:A0A8M3B3R4 | InterPro | 502 | |||||
| UniProtKB:A0A8M3B6M5 | InterPro | 497 | |||||
| UniProtKB:A0A8M3BDF1 | InterPro | 522 | |||||
| UniProtKB:A0A8M9PUH7 | InterPro | 511 | |||||
| UniProtKB:A0A8M9Q6V4 | InterPro | 491 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
camk2b-203
(1)
|
Ensembl | 1,281 nt | ||
| mRNA |
camk2b-204
(1)
|
Ensembl | 489 nt | ||
| mRNA |
camk2b2-201
(1)
|
Ensembl | 943 nt | ||
| mRNA |
camk2b2-202
(1)
|
Ensembl | 495 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers