Gene
crtac1b
- ID
- ZDB-GENE-090312-28
- Name
- cartilage acidic protein 1b
- Symbol
- crtac1b Nomenclature History
- Previous Names
-
- si:dkey-51p7.1
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Predicted to be involved in axonal fasciculation. Orthologous to human CRTAC1 (cartilage acidic protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa1879 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa5867 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa28184 | Allele with one point mutation | Unknown | Missense, Splice Site | ENU | |
| sa45499 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR011519 | ASPIC/UnbV |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Family | IPR027039 | Cartilage acidic protein 1 |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR028994 | Integrin alpha, N-terminal |
| Repeat | IPR013517 | FG-GAP repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | ASPIC/UnbV | Cartilage acidic protein 1 | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | FG-GAP repeat | Growth factor receptor cysteine-rich domain superfamily | Integrin alpha, N-terminal | NOTCH1 EGF-like calcium-binding domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z2E1 | InterPro | 651 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
crtac1b-201
(1)
|
Ensembl | 2,058 nt | ||
| mRNA |
crtac1b-202
(1)
|
Ensembl | 1,869 nt | ||
| mRNA |
crtac1b-203
(1)
|
Ensembl | 1,875 nt | ||
| mRNA |
crtac1b-204
(1)
|
Ensembl | 1,887 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-286O21 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-51P7 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068213109 (1) | 2356 nt | ||
| Genomic | GenBank:BX005216 (2) | 163291 nt | ||
| Polypeptide | UniProtKB:A0A8M6Z2E1 (1) | 651 aa |
- Giffen, K.P., Liu, H., Kramer, K.L., He, D.Z. (2019) Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells. Frontiers in neuroscience. 13:1117
- Boskovic, S., Marín-Juez, R., Jasnic, J., Reischauer, S., El Sammak, H., Kojic, A., Faulkner, G., Radojkovic, D., Stainier, D.Y.R., Kojic, S. (2018) Characterization of zebrafish (Danio rerio) muscle ankyrin repeat proteins reveals their conserved response to endurance exercise. PLoS One. 13:e0204312
- Petit, D., Teppa, E., Mir, A., Vicogne, D., Thisse, C., Thisse, B., Filloux, C., Harduin-Lepers, A. (2015) Integrative view of α2,3-sialyltransferases (ST3Gal) molecular and functional evolution in deuterostomes: significance of lineage specific losses. Mol. Biol. Evol.. 32(4):906-27
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