ZFIN is now using GRCz12tu for Genomic Data
Gene

ndst3

ID
ZDB-GENE-090312-199
Name
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Symbol
ndst3 Nomenclature History
Previous Names
  • si:ch211-152j23.1
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable deacetylase activity and heparan sulfate N-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be active in Golgi apparatus. Is expressed in several structures, including central nervous system; cloacal chamber; fin; olfactory placode; and solid lens vesicle. Orthologous to human NDST3 (N-deacetylase and N-sulfotransferase 3).
Genome Resources
Note
ndst3 is orthologous to NDST3 and NDST4. There appears to have been a tandem duplication after the divergence of ray-finned and lobe-finned fishes.
Comparative Information
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ndst3 Human Ortholog
No data available
Associated With ndst3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000863 Sulfotransferase domain
Domain IPR021930 Heparan sulphate-N-deacetylase, deacetylase domain
Domain IPR056793 Heparan sulfate-N-deacetylase, N-terminal domain
Family IPR037359 Heparan sulfate sulfotransferase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Additional Resources Length Heparan sulfate-N-deacetylase, N-terminal domain Heparan sulfate sulfotransferase Heparan sulphate-N-deacetylase, deacetylase domain P-loop containing nucleoside triphosphate hydrolase Sulfotransferase domain
UniProtKB:A0A8M9PIR7 InterPro 579
UniProtKB:A0A8M9Q484 InterPro 874
UniProtKB:E7F825 InterPro 874
UniProtKB:A0AC58JJU7 InterPro 874
UniProtKB:A0AC58JJW4 InterPro 874
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ndst3-201 (1)
Ensembl
Ensembl 3,481 nt
ZFIN BLAST
mRNA ndst3-202 (1)
Ensembl
Ensembl 2,777 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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