Gene

ndst3

ID
ZDB-GENE-090312-199
Name
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Symbol
ndst3 Nomenclature History
Previous Names
  • si:ch211-152j23.1
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable [heparan sulfate]-glucosamine N-sulfotransferase activity and deacetylase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in central nervous system; dermis; fin; neural rod; and olfactory placode. Orthologous to human NDST3 (N-deacetylase and N-sulfotransferase 3) and NDST4 (N-deacetylase and N-sulfotransferase 4).
Genome Resources
Note
ndst3 is orthologous to NDST3 and NDST4. There appears to have been a tandem duplication after the divergence of ray-finned and lobe-finned fishes.
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ndst3 Human Ortholog
No data available
Associated With ndst3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000863 Sulfotransferase domain
Domain IPR021930 Heparan sulphate-N-deacetylase
Family IPR037359 Heparan sulfate sulfotransferase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Heparan sulfate sulfotransferase Heparan sulphate-N-deacetylase P-loop containing nucleoside triphosphate hydrolase Sulfotransferase domain
UniProtKB:A0A2R8RVF1 772
UniProtKB:E7F825 874
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations