Gene

kcnq5a

ID
ZDB-GENE-090312-185
Name
potassium voltage-gated channel, KQT-like subfamily, member 5a
Symbol
kcnq5a Nomenclature History
Previous Names
  • si:dkey-29l6.1
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to enable calmodulin binding activity and delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within potassium ion transport; regulation of ion transmembrane transport; and transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be integral component of membrane. Is expressed in central nervous system; cerebellum; optic tectum; preoptic area; and telencephalon. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 46. Orthologous to human KCNQ5 (potassium voltage-gated channel subfamily Q member 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Chege et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnq5a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant mental retardation 46 Alliance Mental retardation, autosomal dominant 46 617601
Associated With kcnq5a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005821 Ion transport domain
Domain IPR013821 Potassium channel, voltage dependent, KCNQ, C-terminal
Family IPR003937 Potassium channel, voltage dependent, KCNQ
Family IPR028325 Voltage-gated potassium channel
Family IPR043238 Potassium voltage-gated channel subfamily KQT member 5
Domain Details Per Protein
Protein Length Ion transport domain Potassium channel, voltage dependent, KCNQ Potassium channel, voltage dependent, KCNQ, C-terminal Potassium voltage-gated channel subfamily KQT member 5 Voltage-gated potassium channel
UniProtKB:F1Q5A8 973
UniProtKB:A0A2R8QR27 432
UniProtKB:B8JHS5 929
UniProtKB:F1R7Y2 173
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations