Gene
usp53b
- ID
- ZDB-GENE-090312-168
- Name
- ubiquitin specific peptidase 53b
- Symbol
- usp53b Nomenclature History
- Previous Names
-
- si:ch73-140j6.1
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to be involved in response to auditory stimulus and sensory perception of sound. Predicted to act upstream of or within protein deubiquitination. Predicted to be active in cell-cell junction. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Orthologous to human USP53 (ubiquitin specific peptidase 53).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cholestasis, progressive familial intrahepatic, 7, with or without hearing loss | 619658 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Papain-like cysteine peptidase superfamily | Peptidase C19, ubiquitin carboxyl-terminal hydrolase |
|---|---|---|---|---|
| UniProtKB:A0A8M9Q9H7 | InterPro | 980 | ||
| UniProtKB:A0A8M9PIU5 | InterPro | 299 | ||
| UniProtKB:A0A8M3ASD5 | InterPro | 664 | ||
| UniProtKB:A0A8M2BIB8 | InterPro | 1029 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| lincRNA |
ottdart00000046992
(1)
|
Ensembl | 594 nt | ||
| mRNA |
usp53b-201
(1)
|
Ensembl | 3,000 nt | ||
| mRNA |
usp53b-202
(1)
|
Ensembl | 1,174 nt |
Interactions and Pathways
No data available
Plasmids
No data available