Gene
uba6
- ID
- ZDB-GENE-090312-139
- Name
- ubiquitin like modifier activating enzyme 6
- Symbol
- uba6 Nomenclature History
- Previous Names
-
- si:dkey-82j4.2
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin activating enzyme activity. Predicted to be involved in cellular response to DNA damage stimulus; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm and nucleus. Orthologous to human UBA6 (ubiquitin like modifier activating enzyme 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Anderson et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000594 | THIF-type NAD/FAD binding fold |
| Domain | IPR018965 | Ubiquitin-activating enzyme E1, C-terminal |
| Domain | IPR019572 | Ubiquitin-activating enzyme, SCCH domain |
| Domain | IPR032418 | Ubiquitin-activating enzyme E1, FCCH domain |
| Domain | IPR032420 | Ubiquitin-activating enzyme E1, four-helix bundle |
| Family | IPR000011 | Ubiquitin/SUMO-activating enzyme E1-like |
| Family | IPR018075 | Ubiquitin-activating enzyme E1 |
| Family | IPR045886 | ThiF/MoeB/HesA family |
| Homologous_superfamily | IPR035985 | Ubiquitin-activating enzyme |
| Homologous_superfamily | IPR038252 | Ubiquitin-activating enzyme E1, C-terminal domain superfamily |
| Homologous_superfamily | IPR042063 | Ubiquitin-activating enzyme E1, SCCH domain |
| Homologous_superfamily | IPR042302 | Ubiquitin-activating enzyme E1, FCCH domain superfamily |
| Homologous_superfamily | IPR042449 | Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 |
Domain Details Per Protein
| Protein | Length | ThiF/MoeB/HesA family | THIF-type NAD/FAD binding fold | Ubiquitin-activating enzyme | Ubiquitin-activating enzyme E1 | Ubiquitin-activating enzyme E1, C-terminal | Ubiquitin-activating enzyme E1, C-terminal domain superfamily | Ubiquitin-activating enzyme E1, FCCH domain | Ubiquitin-activating enzyme E1, FCCH domain superfamily | Ubiquitin-activating enzyme E1, four-helix bundle | Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 | Ubiquitin-activating enzyme E1, SCCH domain | Ubiquitin-activating enzyme, SCCH domain | Ubiquitin/SUMO-activating enzyme E1-like |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PY01
|
1027 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-82j4.2-201
(1)
|
Ensembl | 3,427 nt | ||
| mRNA |
uba6-202
(1)
|
Ensembl | 3,063 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance