ZFIN is now using GRCz12tu for Genomic Data
Gene
cacna1hb
- ID
- ZDB-GENE-090312-128
- Name
- calcium channel, voltage-dependent, T type, alpha 1H subunit b
- Symbol
- cacna1hb Nomenclature History
- Previous Names
-
- si:ch211-201p7.4
- si:ch211-22n13.1
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Is expressed in atrium and cardiac ventricle. Human ortholog(s) of this gene implicated in childhood absence epilepsy and primary hyperaldosteronism. Orthologous to human CACNA1H (calcium voltage-gated channel subunit alpha1 H).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial hyperaldosteronism IV | Alliance | Hyperaldosteronism, familial, type IV | 617027 |
| {Epilepsy, childhood absence, susceptibility to, 6} | 611942 | ||
| {Epilepsy, idiopathic generalized, susceptibility to, 6} | 611942 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005821 | Ion transport domain |
| Family | IPR002077 | Voltage-dependent calcium channel, alpha-1 subunit |
| Family | IPR005445 | Voltage-dependent calcium channel, T-type, alpha-1 subunit |
| Family | IPR050599 | Voltage-dependent calcium channel alpha-1 subunit |
| Homologous_superfamily | IPR027359 | Voltage-dependent channel domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ion transport domain | Voltage-dependent calcium channel alpha-1 subunit | Voltage-dependent calcium channel, alpha-1 subunit | Voltage-dependent calcium channel, T-type, alpha-1 subunit | Voltage-dependent channel domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q7Y9 | InterPro | 2102 | |||||
| UniProtKB:A0AC58JG36 | InterPro | 2102 | |||||
| UniProtKB:A0AC58JG58 | InterPro | 2102 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cacna1h-202
(1)
|
Ensembl | 4,788 nt | ||
| mRNA |
cacna1hb-201
(1)
|
Ensembl | 5,045 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers