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ZIRC
ZFIN ID: ZDB-GENE-090312-107
Gene Name: cytochrome P450, family 2, subfamily AE, polypeptide 1
Gene Symbol: cyp2ae1    Nomenclature History

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Previous Name: si:ch211-121b5.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension (multiple); myocardial infarction; and renal fibrosis. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2).
Genome Resources: Alliance (1),  Gene:572114 (1),  Ensembl(GRCz11):ENSDARG00000013524 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa502 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cyp2ae1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cyp2ae1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component cytoplasm (more)
    Molecular Function heme binding (more)
    GO Terms (all 14)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cyp2ae1-201 (1)    Ensembl 1860
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp2ae1 No data available
    MARKER RELATIONSHIPS
    cyp2ae1 Contained in: [BAC] CH211-121B5 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009297119 (1)
    Genomic GenBank:CT997819 (1) 189527 bp
    Select Tool
    Polypeptide UniProtKB:E7FGY5 (1) 497 aa
    Sequence Clusters UniGene:118962 (1)
    Sequence Information (all 10)
    ORTHOLOGY for cyp2ae1 ( Chr: 23 )
    CITATIONS (16)