Gene

dnah12

ID
ZDB-GENE-090311-9
Name
dynein, axonemal, heavy chain 12
Symbol
dnah12 Nomenclature History
Previous Names
  • si:ch73-289a15.4
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Predicted to be involved in cilium movement. Predicted to localize to inner dynein arm. Orthologous to human DNAH12 (dynein axonemal heavy chain 12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dnah12 Human Ortholog
No data available
Associated With dnah12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003593 AAA+ ATPase domain
Domain IPR004273 Dynein heavy chain region D6 P-loop domain
Domain IPR013602 Dynein heavy chain, linker
Domain IPR024317 Dynein heavy chain, AAA module D4
Domain IPR024743 Dynein heavy chain, coiled coil stalk
Domain IPR035699 Dynein heavy chain, hydrolytic ATP-binding dynein motor region
Domain IPR035706 Dynein heavy chain, ATP-binding dynein motor region
Domain IPR041228 Dynein heavy chain, C-terminal domain
Domain IPR041466 Dynein heavy chain, AAA 5 extension domain
Domain IPR041589 Dynein heavy chain 3, AAA+ lid domain
Domain IPR041658 Dynein heavy chain AAA lid domain
Family IPR026983 Dynein heavy chain
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR042219 Dynein heavy chain AAA lid domain superfamily
Homologous_superfamily IPR042222 Dynein heavy chain, domain 2, N-terminal
Homologous_superfamily IPR042228 Dynein heavy chain, linker, subdomain 3
Homologous_superfamily IPR043157 Dynein heavy chain, AAA1 domain, small subdomain
Homologous_superfamily IPR043160 Dynein heavy chain, C-terminal domain, barrel region
Domain Details Per Protein
Protein Length AAA+ ATPase domain Dynein heavy chain Dynein heavy chain 3, AAA+ lid domain Dynein heavy chain, AAA1 domain, small subdomain Dynein heavy chain, AAA 5 extension domain Dynein heavy chain AAA lid domain Dynein heavy chain AAA lid domain superfamily Dynein heavy chain, AAA module D4 Dynein heavy chain, ATP-binding dynein motor region Dynein heavy chain, coiled coil stalk Dynein heavy chain, C-terminal domain Dynein heavy chain, C-terminal domain, barrel region Dynein heavy chain, domain 2, N-terminal Dynein heavy chain, hydrolytic ATP-binding dynein motor region Dynein heavy chain, linker Dynein heavy chain, linker, subdomain 3 Dynein heavy chain region D6 P-loop domain P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M9PZ60 3969
UniProtKB:A0A8M9Q7R5 3220
UniProtKB:A0A8M9P5E8 3969
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dnah12-201 (1) Ensembl 11,637 nt
mRNA dnah12-202 (1) Ensembl 12,060 nt
mRNA dnah12-203 (1) Ensembl 8,904 nt
mRNA dnah12-204 (1) Ensembl 8,964 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations