Gene

ugp2a

ID

ZDB-GENE-090311-46

Name

UDP-glucose pyrophosphorylase 2a

Symbol

ugp2a Nomenclature History

Previous Names

si:ch73-233a22.2

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have UTP:glucose-1-phosphate uridylyltransferase activity. Predicted to be involved in UDP-glucose metabolic process and glycogen metabolic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Orthologous to human UGP2 (UDP-glucose pyrophosphorylase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Shao et al., 2022

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ugp2a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 83	Alliance	Developmental and epileptic encephalopathy 83	618744

Associated With ugp2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR002618	UDPGP family
Family	IPR016267	UTP--glucose-1-phosphate uridylyltransferase
Homologous_superfamily	IPR029044	Nucleotide-diphospho-sugar transferases