Gene
arhgap4b
- ID
- ZDB-GENE-090311-38
- Name
- Rho GTPase activating protein 4b
- Symbol
- arhgap4b Nomenclature History
- Previous Names
-
- si:dkey-95f11.4
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of cell migration; nervous system development; and regulation of synapse assembly. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human ARHGAP4 (Rho GTPase activating protein 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000198 | Rho GTPase-activating protein domain |
| Domain | IPR001060 | FCH domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR031160 | F-BAR domain |
| Family | IPR051627 | SLIT-ROBO Rho GTPase-activating |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR027267 | AH/BAR domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | AH/BAR domain superfamily | F-BAR domain | FCH domain | Rho GTPase-activating protein domain | Rho GTPase activation protein | SH3 domain | SH3-like domain superfamily | SLIT-ROBO Rho GTPase-activating |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B8X5 | InterPro | 943 | ||||||||
| UniProtKB:A0A8M3AY98 | InterPro | 951 | ||||||||
| UniProtKB:A0A8M3AV78 | InterPro | 531 | ||||||||
| UniProtKB:E7FEI6 | InterPro | 966 | ||||||||
| UniProtKB:A0AB32TAT5 | InterPro | 928 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arhgap4b-201
(1)
|
Ensembl | 2,901 nt | ||
| mRNA |
arhgap4b-202
(1)
|
Ensembl | 4,044 nt |
Interactions and Pathways
No data available
Plasmids
No data available