Gene
tcirg1a
- ID
- ZDB-GENE-090311-31
- Name
- T cell immune regulator 1, ATPase H+ transporting V0 subunit a3a
- Symbol
- tcirg1a Nomenclature History
- Previous Names
-
- tcirg1
- si:dkey-9i23.9
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable ATPase binding activity. Predicted to be involved in vacuolar acidification. Predicted to act upstream of or within proton transmembrane transport. Predicted to be located in membrane. Predicted to be part of vacuolar proton-transporting V-type ATPase complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 1. Orthologous to human TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive osteopetrosis 1 | Alliance | Osteopetrosis, autosomal recessive 1 | 259700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ATPase, V0 complex, subunit 116kDa, eukaryotic | V-type ATPase, V0 complex, 116kDa subunit family |
|---|---|---|---|
|
UniProtKB:B8A655
|
823 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tcirg1a-201
(1)
|
Ensembl | 3,339 nt | ||
| mRNA |
tcirg1a-202
(1)
|
Ensembl | 2,469 nt |
Interactions and Pathways
No data available
Plasmids
No data available