Gene

card14

ID
ZDB-GENE-090310-1
Name
caspase recruitment domain family, member 14
Symbol
card14 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have CARD domain binding activity. Predicted to be involved in regulation of apoptotic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in pityriasis rubra pilaris and psoriasis 2. Is expressed in gill and spleen. Orthologous to human CARD14 (caspase recruitment domain family member 14).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Chang et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With card14 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pityriasis rubra pilaris Alliance Pityriasis rubra pilaris 173200
psoriasis 2 Alliance Psoriasis 2 602723
Associated With card14 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001315 CARD domain
Homologous_superfamily IPR011029 Death-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length CARD domain Death-like domain superfamily PDZ superfamily P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8N7T7Y7 985
UniProtKB:A0A8M9Q0C3 985
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA card14-201 (1) Ensembl 4,099 nt
mRNA card14-202 (1) Ensembl 6,327 nt
mRNA card14-203 (1) Ensembl 6,542 nt
mRNA card14-204 (1) Ensembl 6,924 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations