Gene
card14
- ID
- ZDB-GENE-090310-1
- Name
- caspase recruitment domain family, member 14
- Symbol
- card14 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within regulation of apoptotic process. Predicted to be located in membrane. Is expressed in gill and spleen. Human ortholog(s) of this gene implicated in pityriasis rubra pilaris and psoriasis 2. Orthologous to human CARD14 (caspase recruitment domain family member 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chang et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pityriasis rubra pilaris | Alliance | Pityriasis rubra pilaris | 173200 |
| psoriasis 2 | Alliance | Psoriasis 2 | 602723 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CARD domain | Death-like domain superfamily | PDZ superfamily | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|
|
UniProtKB:A0A8N7T7Y7
|
985 | ||||
|
UniProtKB:A0A8M9Q0C3
|
985 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
card14-201
(1)
|
Ensembl | 4,099 nt | ||
| mRNA |
card14-202
(1)
|
Ensembl | 6,327 nt | ||
| mRNA |
card14-203
(1)
|
Ensembl | 6,542 nt | ||
| mRNA |
card14-204
(1)
|
Ensembl | 6,924 nt |
Interactions and Pathways
No data available
Plasmids
No data available