Gene

mcama

ID
ZDB-GENE-090218-29
Name
melanoma cell adhesion molecule a
Symbol
mcama Nomenclature History
Previous Names
  • im:7151111
  • im:7163338
  • zmp:0000001063
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable laminin receptor activity. Predicted to be involved in angiogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in myotome; nervous system; pharyngeal arch; and somite. Orthologous to human MCAM (melanoma cell adhesion molecule).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa18255Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa40577Allele with one point mutationUnknownSplice SiteENU
Zebrafish International Resource Center (ZIRC) (order this)
1 - 2 of 2
Show
Sequence Targeting Reagents
No data available
Human Disease
Associated With mcama Human Ortholog
No data available
Associated With mcama Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin domain subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013106 Immunoglobulin V-set domain
Domain IPR013151 Immunoglobulin-like beta-sandwich domain
1 - 5 of 9 Show all
Domain Details Per Protein
Protein Additional Resources Length CD80-like, immunoglobulin C2-set Cell Surface Receptors and Adhesion Molecules Immunoglobulin domain subtype Immunoglobulin-like beta-sandwich domain Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype 2 Immunoglobulin V-set domain
UniProtKB:A0A8M3B2W5 InterPro 634
UniProtKB:A0A8M9P925 InterPro 634
UniProtKB:A0AB32TET1 InterPro 633
UniProtKB:A0AB32TET2 InterPro 629
UniProtKB:A0AB32TLN7 InterPro 638
1 - 5 of 8 Show all
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mcama-201 (1)
Ensembl
Ensembl 5,105 nt
ZFIN BLAST
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-70K11
Contained inBACDKEY-85K22
EncodesESTIMAGE:7151111Thisse et al., 2004
EncodesESTIMAGE:7163338Thisse et al., 2004
1 - 4 of 4
Show
Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_009301889 (1)5135 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:BX248506 (1)226627 nt
MegaBLAST
PolypeptideUniProtKB:A0AB32TLN7 (1)638 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanMCAM11
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
TSV
1 - 2 of 2
Show
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.