Gene
grem1b
- ID
- ZDB-GENE-090218-21
- Name
- gremlin 1b
- Symbol
- grem1b Nomenclature History
- Previous Names
-
- sb:eu2461
- si:ch1073-209e23.2
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable BMP binding activity and receptor ligand activity. Predicted to be involved in sequestering of BMP from receptor via BMP binding activity. Predicted to be active in extracellular space. Is expressed in musculature system; myotome; pectoral fin; pharyngeal arch; and somite. Orthologous to human GREM1 (gremlin 1, DAN family BMP antagonist).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu2461 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cystine knot, C-terminal | Cystine-knot cytokine | DAN |
|---|---|---|---|---|---|
| UniProtKB:A0A8M9PKX9 | InterPro | 204 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
grem1b-201
(1)
|
Ensembl | 2,507 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | Fosmid | CH1073-209E23 | ZFIN Curated Data | |
| Encodes | EST | eu2461 | Thisse et al., 2005 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_021467246 (1) | |||
| Genomic | GenBank:CU693366 (2) | 31475 nt | ||
| Polypeptide | UniProtKB:A0A8M9PKX9 (1) | 204 aa |
- Demirci, Y., Cucun, G., Poyraz, Y.K., Mohammed, S., Heger, G., Papatheodorou, I., Ozhan, G. (2020) Comparative Transcriptome Analysis of the Regenerating Zebrafish Telencephalon Unravels a Resource With Key Pathways During Two Early Stages and Activation of Wnt/β-Catenin Signaling at the Early Wound Healing Stage. Frontiers in cell and developmental biology. 8:584604
- Witjes, L., Van Troys, M., Vandekerckhove, J., Vandepoele, K., Ampe, C. (2019) A new evolutionary model for the vertebrate actin family including two novel groups. Molecular phylogenetics and evolution. 141:106632
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