ZFIN ID: ZDB-GENE-081215-2
Gene Name: sprouty homolog 1, antagonist of FGF signaling (Drosophila)
Gene Symbol: spry1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: sprouty1 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to be involved in negative regulation of MAP kinase activity; negative regulation of Ras protein signal transduction; and negative regulation of fibroblast growth factor receptor signaling pathway. Predicted to localize to the cytosol. Is expressed in several structures, including fin; gill; hindbrain neural keel; mesoderm; and nervous system. Orthologous to human SPRY1 (sprouty RTK signaling antagonist 1).
Genome Resources: Alliance (1),  Gene:798229 (1),  Ensembl(GRCz11):ENSDARG00000103985 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-spry1 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH spry1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH spry1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process multicellular organism development (more)
Cellular Component membrane (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR007875 Sprouty
Family IPR030783 Protein sprouty homologue 1
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM spry1 No data available
MARKER RELATIONSHIPS No data available
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001122600 (1)
Genomic GenBank:CABZ01118379 (1) 4447 nt
Polypeptide UniProtKB:B1PBZ7 (1) 292 aa
Sequence Information (all 10)
ORTHOLOGY for spry1 ( Chr: 14 )
CITATIONS (20)