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ZIRC
ZFIN ID: ZDB-GENE-081211-2
Gene Name: lysocardiolipin acyltransferase 1
Gene Symbol: lclat1    Nomenclature History

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Previous Names: lycat (1), wu:fj17g04, zgc:77380

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have 1-acylglycerol-3-phosphate O-acyltransferase activity. Involved in endothelial cell development and hemangioblast cell differentiation. Predicted to localize to the endoplasmic reticulum. Is expressed in hematopoietic stem cell. Orthologous to human LCLAT1 (lysocardiolipin acyltransferase 1).
Genome Resources: Alliance (1),  Gene:406554 (1),  Ensembl(GRCz11):ENSDARG00000103320 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-lclat1
1
CRISPR2-lclat1
1
MO1-lclat1 N/A 3
MO2-lclat1 N/A 2
MO3-lclat1 N/A 3
DISEASE ASSOCIATED WITH lclat1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH lclat1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic hemopoiesis (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function 1-acylglycerol-3-phosphate O-acyltransferase activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002123 (1)
  • InterPro:IPR032098 (1)
  • Pfam:PF01553 (1)
  • Pfam:PF16076 (1)
  • EC:2.3.1.51 (1)
  • TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lclat1 No data available
    MARKER RELATIONSHIPS
    lclat1 Encodes: [EST] fj17g04 (1)
    [cDNA] MGC:77380 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213270 (1)
    Polypeptide UniProtKB:Q6NYV8 (1) 388 aa
    Sequence Clusters UniGene:80904 (1)
    Sequence Information (all 11)
    ORTHOLOGY for lclat1 ( Chr: 13 )
    CITATIONS (121)