ZFIN is now using GRCz12tu for Genomic Data
Gene
ppp3r1a
- ID
- ZDB-GENE-081113-3
- Name
- protein phosphatase 3, regulatory subunit B, alpha a
- Symbol
- ppp3r1a Nomenclature History
- Previous Names
-
- ppp3r1
- si:ch211-274c22.8
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium-dependent protein serine/threonine phosphatase regulator activity and phosphatase binding activity. Predicted to be involved in calcineurin-mediated signaling. Predicted to be part of calcineurin complex. Is expressed in brain; heart; inner ear; and swim bladder. Human ortholog(s) of this gene implicated in Alzheimer's disease and dilated cardiomyopathy. Orthologous to several human genes including PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair |
|---|---|---|---|---|---|
| UniProtKB:A0A8M3BEF6 | InterPro | 175 | |||
| UniProtKB:E9QG20 | InterPro | 170 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppp3r1a-201
(1)
|
Ensembl | 1,203 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers