Gene
ppp3r1a
- ID
- ZDB-GENE-081113-3
- Name
- protein phosphatase 3, regulatory subunit B, alpha a
- Symbol
- ppp3r1a Nomenclature History
- Previous Names
-
- ppp3r1
- si:ch211-274c22.8
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable calcium-dependent protein serine/threonine phosphatase regulator activity and phosphatase binding activity. Predicted to be involved in calcineurin-mediated signaling and protein dephosphorylation. Predicted to be part of calcineurin complex. Is expressed in brain. Human ortholog(s) of this gene implicated in Alzheimer's disease and dilated cardiomyopathy. Orthologous to several human genes including PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair |
|---|---|---|---|---|
|
UniProtKB:A0A8M3BEF6
|
175 | |||
|
UniProtKB:E9QG20
|
170 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppp3r1a-201
(1)
|
Ensembl | 1,203 nt |
Interactions and Pathways
No data available
Plasmids
No data available