Gene
si:ch73-105b23.6
- ID
- ZDB-GENE-081107-42
- Name
- si:ch73-105b23.6
- Symbol
- si:ch73-105b23.6 Nomenclature History
- Previous Names
-
- zmp:0000000902
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have ErbB-2 class receptor binding activity; calcium ion binding activity; and extracellular matrix constituent, lubricant activity. Predicted to be involved in regulation of signaling receptor activity. Predicted to localize to extracellular space and integral component of membrane. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human MUC4 (mucin 4, cell surface associated).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Gehlen et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Gehlen et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR013032 | EGF-like, conserved site |
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001846 | von Willebrand factor, type D domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR003886 | NIDO domain |
| Domain | IPR005533 | AMOP domain |
| Domain | IPR024731 | EGF domain |
| Domain | IPR026823 | Complement Clr-like EGF domain |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Family | IPR051495 | Epithelial Barrier and Cell Signaling Protein |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Length | AMOP domain | Complement Clr-like EGF domain | EGF domain | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like, conserved site | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Epithelial Barrier and Cell Signaling Protein | Growth factor receptor cysteine-rich domain superfamily | NIDO domain | NOTCH1 EGF-like calcium-binding domain | von Willebrand factor, type D domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PYY3
|
2596 | |||||||||||||
|
UniProtKB:A0A8M6Z9Q8
|
762 | |||||||||||||
|
UniProtKB:E7FG10
|
762 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch73-105b23.6-201
(1)
|
Ensembl | 2,453 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance